August 3, 2010
IBM scientists study deep-sea mud juice with atomic force microscope, find orchid juice
The discovery of novel chemical compounds is a huge part of modern pharmaceutical research. The problem is, there aren't too many novel places left on the globe left to look. One of the least studied is at the deepest place on Earth, the bottom of the Mariana Trench, and that's just where researchers at the University of Aberdeen found some mud to play with. However, they weren't able to accurately identify the compounds found in the pile of trench goop they were analyzing. A call to scientists at IBM Zurich resulted in an opportunity to play with their atomic force microscope, a device that uses a tiny probe with a tip that that actually "feels" the surface of whatever you're looking at. With this the team was able to determine the nature of the compounds being generated by bacteria in the mud: cephalandole A, also generated by the Taiwanese orchid Cephalanceropsis gracilis. Now, instead of getting your significant other a beautiful orchid for some special occasion you can fill a vase with mud and romantically explain how they both generate the same basic compounds.
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